HORDB

General Information

ID: hor003224
Uniprot ID: NA
Protein name: Enkephalin
Gene name: NA
Organism: Oryctolagus cuniculus
Family: Opioid neuropeptide precursor family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: YSGFLT
Length: 6
Propeptide: NA
Signal peptide: NA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Activity

Function: NA
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor003224_AF2.pdb

hor003224_ESM.pdb

Physical Information

Mass:	77612	Formula:	C33H46N6O10
Absent amino acids:	ACDEHIKMNPQRVW	Common amino acids:	FGLSTY
pI:	6.09	Basic residues:	0
Polar residues:	4	Hydrophobic residues:	2
Hydrophobicity:	56.67	Boman Index:	273
Half-Life:	2.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	2 min	Aliphatic Index	65
Instability Index:	833.33	Extinction Coefficient cystines:	1490
Absorbance 280nm:	298

Literature

PubMed ID: 6306437
Title: Multiple Opiate Binding Sites in the Central Nervous System of the Rabbit. Large Predominance of a Mu Subtype in the Cerebellum and Characterization of a Kappa Subtype in the Thalamus